Table 4 Factors for an elevation of serum creatinine levels of 20% or more
From: Impact of intensive care on renal function before graft harvest: results of a monocentric study
Elevation of serum creatinine levels | ||
|---|---|---|
<20% (n = 85) | >20% (n = 58) | |
Demographic data | ||
Women, number (percentage) | 36 (42) | 18 (31) |
Age (years) (mean ± SD) | 39 ± 14 | 38 ± 13 |
Causes of ICU admission | ||
Head trauma, number (percentage) | 37 (43) | 33 (57) |
Intracranial bleeding, number (percentage) | 37 (44) | 20 (36) |
Cerebral anoxia, number (percentage) | 6 (8) | 2 (3) |
Suicide, number (percentage) | 5 (6) | 3 (5) |
ICU steps | ||
Duration of stay in ICU (hours) (mean ± SD) | 63 ± 56 | 80 ± 72 |
Duration of brain death (hours) (mean ± SD) | 27 ± 11 | 34 ± 17a |
Duration of brain death >24 hours, number (percentage) | 45 (53) | 44 (76)a |
Catecholamines | ||
Dopamine, number (percentage) | 26 (31) | 11 (19) |
Dobutamine, number (percentage) | 5 (6) | 6 (10) |
Epinephrine, number (percentage) | 28 (33) | 23 (40) |
Norepinephrine, number (percentage) | 58 (68) | 43 (74) |
Fluid expansion | ||
Isotonic saline solution (mL) (mean ± SD) | 3,406 ± 3,825 | 4,020 ± 4,259 |
Lactate ringer (mL) (mean ± SD) | 2,696 ± 2,641 | 2,413 ± 2,546 |
Gelatin (mL) (mean ± SD) | 441 ± 930 | 452 ± 933 |
Hydroxyethylstarch, number (percentage) | 67 (79) | 46 (79) |
Hydroxyethylstarch (mL) (mean ± SD) | 1,047 ± 1,019 | 1,349 ± 1,148 |
Osmotherapy | ||
Mannitol 20% (mL) (mean ± SD) | 123 ± 221 | 276 ± 241a |
Hypertonic saline solution 7.5% (mL) (mean ± SD) | 111 ± 235 | 159 ± 369 |
Urine output modulators | ||
Furosemide, number (percentage) | 19 (22) | 17 (29) |
Furosemide (mg) (mean ± SD) | 14 ± 57 | 17 ± 42 |
Desmopressin, number (percentage) | 68 (80) | 46 (79) |
Desmopressin (μg) (mean ± SD) | 5.7 ± 6.2 | 6.2 ± 5.1 |
Hemodynamic profile | ||
Cardiac arrest, number (percentage) | 16 (19) | 10 (17) |
Shock, number (percentage) | 53 (62) | 40 (69) |
Duration of shock (minutes) (mean ± SD) | 65 ± 108 | 102 ± 180 |
MAP upon admission (mm Hg) (mean ± SD) | 91 ± 25 | 87 ± 25 |
Preharvesting MAP (mm Hg) (mean ± SD) | 81 ± 17 | 81 ± 18 |
Respiratory profile | ||
Acute respiratory distress syndrome, number (percentage) | 22 (26) | 23 (40) |
Acute lung injury, number (percentage) | 21 (25) | 11 (19) |
Characteristics of renal function | ||
Oliguria, number (percentage) | 39 (46) | 27 (47) |
Serum creatinine upon admission (μmol/L) (mean ± SD) | 95 ± 42 | 80 ± 28a |
Preharvesting serum creatinine (μmol/L) (mean ± SD) | 82 ± 40 | 121 ± 76a |
Acidosis (pH <7.30), number (percentage) | 23 (27) | 22 (38) |
Disseminated intravascular coagulation, number (percentage) | 11 (13) | 13 (22) |
Injection of contrast, number (percentage) | 52 (61) | 45 (78)a |