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Table 1 Baseline characteristics and clinical risk conditions: ICU and ward

From: Clinical risk conditions for acute lung injury in the intensive care unit and hospital ward: a prospective observational study

Characteristic or condition All patients ICU admissions Non-ICU admissions P a
Number 815 108 707  
Age, years; median (interquartile range) 74 (55–83) 66 (48–78) 74 (56–84) <0.001
Female sex, n (percentage) 450 (55.2) 61 (56.5) 389 (55.0) 0.836
McCabe score     
Non-fatal 618 (75.8) 81 (75.0) 537 (76.0)  
Ultimately fatal 178 (21.8) 25 (23.1) 153 (21.6) 0.894
Fatal 19 (2.3) 2 (1.9) 17 (2.4)  
Medical (versus surgical) admission 663 (81.3) 56 (51.9) 607 (85.9) <0.001
Clinical risk conditions, n (percentage)     
Sepsis 704 (86.4) 84 (77.8) 620 (87.7) 0.005
Pneumonia 233 (28.6) 30 (27.8) 203 (28.7) 0.841
Aspiration 16 (2.0) 1 (0.9) 15 (2.1) 0.709
Trauma 21 (2.6) 3 (2.8) 18 (2.5) 0.751
Transfusions 9 (1.1) 8 (7.4) 1 (0.1) <0.001
Pancreatitis 75 (9.2) 3 (2.8) 72 (10.2) 0.011
Pulmonary contusion 3 (0.4) 2 (1.9) 1 (0.1) 0.048
Shock 59 (7.2) 51 (47.2) 8 (1.1) <0.001
Other 2 (0.2) 2 (1.9) 0 0.017
Any pulmonary insult 244 (29.9) 34 (31.5) 210 (29.7) 0.707
On day of clinical risk development, median (IQR) or n (percentage)     
SAPS II 26 (18–33) 40 (27–49) 28 (22–35) <0.001
MAP 84 (74.8–95) 70 (56–83) 89 (77.8–100) <0.001
GCS 15 (15–15) 15 (15–15) 15 (15–15) 0.647
PaO2/FiO2, mmHg 261.9 (221–310) 217.1 (158–323) 266.7 (238–314) <0.001
   Vasoactive drugs 40 (4.9) 40 (37.0) 0 <0.001
Mechanical ventilation 46 (5.6) 46 (42.6) 0 <0.001
Location (on ward) 730 (89.6) 23 (21.5) 707 (100) <0.001
   MODS score 1.0 (0–3) 5 (3–7) 2 (1–3) <0.001
Days from hospital admission to insult 0 (0–1) 0 (0–5) 0 (0–0) 0.041
ALI diagnosis 20 (2.5) 9 (8.3) 11 (1.6) <0.001
ARDS diagnosis 33 (4.0) 29 (26.8) 4 (0.6) <0.001
  1. ICU, intensive care unit; IQR, interquartile range; ALI, acute lung injury (PaO2/FiO2 200 to 300 mmHg); ARDS, acute respiratory distress syndrome; SAPS, simplified acute physiology score; MAP, mean arterial pressure; GCS, Glasgow coma score; PaO2, partial pressure of arterial oxygen; FiO2, fractional concentration of inspired oxygen; MODS, multiple organ dysfunction syndrome. aComparing ICU admissions with non-ICU admissions