Usefulness of open lung biopsy in mechanically ventilated patients with undiagnosed diffuse pulmonary infiltrates: influence of comorbidities and organ dysfunction

Table 4 Univariate analysis of variables associated with mortality

Variable	P	Odds ratio	95% CI
CCS	0.041	1.57	1.02–2.43
Number of organ dysfunctions	0.047	2.85	1.02–8.01
SOFA_olb	0.013	1.55	1.10–2.19
SOFA_max	0.055	1.30	0.99–1.70
PaO₂/FiO₂ ratioon OLB day	0.023	0.985	0.973–0.998
Time to OLB, days	0.086	1.18	0.98–1.43
OLB complication	0.184	2.50	0.65–9.65
Immunocompromised status	0.146	0.31	0.67–1.50

CCS, Charlson age–comorbidity score; SOFA_olb, SOFA (Sequential Organ Failure Assessment) score at the day of open lung biopsy; SOFA_max, maximum SOFA score; OLB, open lung biopsy; time to OLB, days from mechanical ventilation to OLB; CI, confidence interval.

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