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Table 3 A comparison between survivors and non-survivors

From: Usefulness of open lung biopsy in mechanically ventilated patients with undiagnosed diffuse pulmonary infiltrates: influence of comorbidities and organ dysfunction

Characteristic

Survivor group (n = 18)

Non-survivor group (n = 18)

P

Age, years

54.5 ± 14.7

57.3 ± 15.2

0.580

Sex

   

   Male

11 (61.1)

14 (77.8)

0.471

   Female

7 (38.9)

4 (22.2)

 

BMI, kg/m2

22.9 ± 2.3

21.7 ± 3.1

0.283

Smoking, pack-years

21.8 ± 23.6

19.9 ± 20.7

0.873

Duration of symptom, days

21.7 ± 33.5

15.2 ± 13.1

0.888

CCS

1.9 ± 1.3

3.2 ± 2.1

0.030

SAPS II score

35.2 ± 9.3

37.6 ± 7.9

0.425

APACHE II score

16.9 ± 5.4

17.6 ± 4.9

0.700

Time to OLB, days

3.8 ± 2.0

6.8 ± 6.4

0.061

OLB time, early/late

17/1

10/8

0.018

Immunocompromised status

3 (17)

7 (39)

0.137

OLB complication

8 (44)

12 (67)

0.180

Ventilation duration, days

14.9 ± 15.5

19.9 ± 12.0

0.282

Number of organ dysfunctions

   

   On MICU admission

1.5 ± 0.6

1.7 ± 0.7

0.308

   On day of OLB

1.5 ± 0.6

2.0 ± 0.8

0.039

SOFA score

   

   On MICU admission

5.3 ± 2.5

6.2 ± 2.3

0.249

   On day of OLB

4.3 ± 2.1

6.7 ± 2.7

0.005

   Maximum

6.1 ± 2.7

8.1 ± 2.9

0.042

PaO2/FiO2ratio

   

   On MICU admission

131.3 ± 37.1

118.9 ± 55.9

0.439

   On day of OLB

190.6 ± 67.6

135.4 ± 57.4

0.012

PEEP, cmH2O

   

   On MICU admission

10.2 ± 3.1

11.3 ± 4.2

0.381

   On day of OLB

9.4 ± 4.3

11.3 ± 2.4

0.112

Compliance, ml/cmH2O

   

   On MICU admission

16.7 ± 7.7

15.8 ± 5.5

0.703

   On day of OLB

17.1 ± 8.4

15.5 ± 7.5

0.550

  1. Data are presented as mean ± SD or n (%). BMI, body mass index; CCS, Charlson age–comorbidity score; SAPS, Simplified Acute Physiology Score; APACHE II, Acute Physiologic and Chronic Health Evaluation II; OLB, open lung biopsy; early OLB, OLB within 1 week of mechanical ventilation; MICU, medical intensive care unit; SOFA, Sequential Organ Failure Assessment; PEEP, positive end-expiratory pressure.