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Table 3 A comparison between survivors and non-survivors

From: Usefulness of open lung biopsy in mechanically ventilated patients with undiagnosed diffuse pulmonary infiltrates: influence of comorbidities and organ dysfunction

Characteristic Survivor group (n = 18) Non-survivor group (n = 18) P
Age, years 54.5 ± 14.7 57.3 ± 15.2 0.580
Sex    
   Male 11 (61.1) 14 (77.8) 0.471
   Female 7 (38.9) 4 (22.2)  
BMI, kg/m2 22.9 ± 2.3 21.7 ± 3.1 0.283
Smoking, pack-years 21.8 ± 23.6 19.9 ± 20.7 0.873
Duration of symptom, days 21.7 ± 33.5 15.2 ± 13.1 0.888
CCS 1.9 ± 1.3 3.2 ± 2.1 0.030
SAPS II score 35.2 ± 9.3 37.6 ± 7.9 0.425
APACHE II score 16.9 ± 5.4 17.6 ± 4.9 0.700
Time to OLB, days 3.8 ± 2.0 6.8 ± 6.4 0.061
OLB time, early/late 17/1 10/8 0.018
Immunocompromised status 3 (17) 7 (39) 0.137
OLB complication 8 (44) 12 (67) 0.180
Ventilation duration, days 14.9 ± 15.5 19.9 ± 12.0 0.282
Number of organ dysfunctions    
   On MICU admission 1.5 ± 0.6 1.7 ± 0.7 0.308
   On day of OLB 1.5 ± 0.6 2.0 ± 0.8 0.039
SOFA score    
   On MICU admission 5.3 ± 2.5 6.2 ± 2.3 0.249
   On day of OLB 4.3 ± 2.1 6.7 ± 2.7 0.005
   Maximum 6.1 ± 2.7 8.1 ± 2.9 0.042
PaO2/FiO2ratio    
   On MICU admission 131.3 ± 37.1 118.9 ± 55.9 0.439
   On day of OLB 190.6 ± 67.6 135.4 ± 57.4 0.012
PEEP, cmH2O    
   On MICU admission 10.2 ± 3.1 11.3 ± 4.2 0.381
   On day of OLB 9.4 ± 4.3 11.3 ± 2.4 0.112
Compliance, ml/cmH2O    
   On MICU admission 16.7 ± 7.7 15.8 ± 5.5 0.703
   On day of OLB 17.1 ± 8.4 15.5 ± 7.5 0.550
  1. Data are presented as mean ± SD or n (%). BMI, body mass index; CCS, Charlson age–comorbidity score; SAPS, Simplified Acute Physiology Score; APACHE II, Acute Physiologic and Chronic Health Evaluation II; OLB, open lung biopsy; early OLB, OLB within 1 week of mechanical ventilation; MICU, medical intensive care unit; SOFA, Sequential Organ Failure Assessment; PEEP, positive end-expiratory pressure.