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Figure 1 | Critical Care

Figure 1

From: Involvement of Akt and endothelial nitric oxide synthase in ventilation-induced neutrophil infiltration: a prospective, controlled animal experiment

Figure 1

High tidal volume ventilation caused a time-dependent increase on Akt activation. Western blot was performed using an antibody that recognizes the phosphorylated serine/threonine kinase/protein kinase B (Akt) expression ((a) and (b), top panel) and an antibody that recognizes total Akt protein expressions in lung tissue ((a) and (b), middle panel) from control nonventilated mice and from mice ventilated with tidal volume 30 ml/kg breathing room air or hyperoxia at indicated time periods. RA, mice with room air; O2, mice with hyperoxia. Arbitrary units are expressed as relative Akt phosphorylation ((a) and (b), bottom panel) (n = 6/group). *P < 0.05 versus control, nonventilated mice.

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Critical Care

ISSN: 1364-8535