Table 2 Blood mitochondrial DNA/nuclear DNA ratio in short-term survivors versus non-survivors
No adjustment | Adjusted for platelet count | |||||
|---|---|---|---|---|---|---|
mtDNA/nDNA ratio | Survivors (N = 16) | Non-survivors (N = 12) | P value | Survivors (N = 16) | Non-survivors (N = 12) | P value |
At baseline | 0.74 ± 0.05 | 0.79 ± 0.06 | 0.49 | 0.74 ± 0.05 | 0.79 ± 0.06 | 0.49 |
At day 4 (± 1) | 0.94 ± 0.08 | 0.73 ± 0.09 | 0.10 | 0.95 ± 0.08 | 0.72 ± 0.10 | 0.10 |
At last measurement | 0.98 ± 0.06 | 0.79 ± 0.07 | 0.04 | 0.97 ± 0.06 | 0.79 ± 0.07 | 0.05 |
Change at day 4 (± 1) | +29.5 ± 10.1 | -5.7 ± 11.6 | 0.03 | +30.3 ± 10.3 | -6.6 ± 11.9 | 0.03 |
Change at last measurement | +38.4 ± 10.5 | +7.1 ± 12.1 | 0.06 | +36.5 ± 10.4 | +9.7 ± 12.0 | 0.11 |