Skip to main content

Table 2 Results of the inflammatory mediators and cardiac troponin I

From: Influence of dextran-70 on systemic inflammatory response and myocardial ischaemia-reperfusion following cardiac operations

 

t1

t2

t3

t4

t5

t6

p

C-reactive protein (mg/l)

   Group A

3.7 (1.0–22.6)

   

79.9 (50.0–131.7)

112.0 (61.1–177.6)

<0.001

   Group B

2.6 (0.6–10.5)

   

87.6 (52.4–143.0)

131.0 (71.0–228.0)

<0.001

 

p = 0.068*

   

p = 0.092*

p = 0.168*

 

IL-6 (pg/ml)

       

   Group A

1.6 (0.4–21.8)

 

95.0 (13.6–405.1)

46.3 (16.1–149.5)

  

<0.001

   Group B

2.0 (0.4–60.6)

 

130.5 (21.7–353.8)

49.2 (14.8–214.5)

  

<0.001

 

p = 0.107*

 

p = 0.829*

p = 0.482*

   

IL-6r (ng/ml)

       

   Group A

43.6 (1.7–125.0)

 

47.4 (0.7–109.5)

56.2 (25.2–226.3)

  

0.949

   Group B

40.7 (15.6–94.6)

 

42.4 (22.2–100.5)

50.2 (13.2–104.9)

  

0.861

 

p = 0.607*

 

p = 0.914*

p = 0.304*

   

IL-10 (pg/ml)

       

   Group A

1.9 (0.2–24.0)

47.2 (2.3–476.6)

7.2 (1.3–90.9)

   

<0.001

   Group B

2.6 (0.8–9.7)

209.7 (16.3–814.3)

56.1 (3.6–225.1)

   

<0.001

 

p = 0.136*

p = 0.001*

p = 0.001*

    

Soluble endothelial leukocyte adhesion molecule-1 (ng/ml)

   Group A

88.6 (49.8–194.5)

  

88.5 (14.4–189.6)

72.7 (8.9–163.1)

 

0.058

   Group B

49.0 (18.3–144.1)

  

130.7 (33.0–360.7)

72.6 (16.7–224.7)

 

<0.001

 

p < 0.001*

  

p = 0.033*

p = 0.957*

  

Cardiac troponin-I (ng/ml)

   Group A

0.02 (0.01–0.022)

   

0.22 (0.07–0.85)

0.13 (0.03–0.75)

<0.001

   Group B

0.01 (0.01–0.016)

   

0.66 (0.10–1.28)

0.19 (0.03–0.80)

<0.001

 

p = 0.520*

   

p = 0.018*

p = 0.097*

 
  1. Data presented as the median (range). t1, before anaesthesia; t2, 10 minutes after cardiac surgery on cardiopulmonary bypass (CPB); t3, 2 hours after CPB; t4, 4 hours after CPB; t5, 24 hours after CPB; t6, 44 hours after CPB. Intraindividual differences (Friedman test), *between-group differences (Kruskal–Wallis test).