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Table 1 Respiratory mechanics and regression parameters

From: Positive end-expiratory pressure at minimal respiratory elastance represents the best compromise between mechanical stress and lung aeration in oleic acid induced lung injury

Parameter Descending PEEP titration steps
PEEPappl (cmH2O) 27.1 (25.3–27.7) 21.0 (19.8–22.1) 16.3 (15.6–17.2) 12.3 (12–13.1) 8.4 (7.7–9.2) 6.2 (5.9–6.9) 0.8 (0.5–1.7)
Ppeak (cmH2O) 47.85 (40–52) 36.4 (31.3–40.5) 29.35 (25.7–30.6) 25.1 (22.6–28.2) 24.05 (21.3–26.4) 23.7 (20.7–25.7) 24 (21.6–28.8)
Pplateau (cmH2O) 39.5 (33.8–45.6) 31.2 (28.9–37.5) 25.6 (24.4–28.1) 21.3 (19.2–25.1) 19.1 (17–22.4) 18.1 (16.3–22.2) 17.9 (14.2–21.4)
Ers (cmH2O.l-1) 131.4 (90.1–141.4) 84.0 (65.1–101) 65.5 (54.9–81.5) 70.4 (53–95.9) 86.4 (67.5–129.2) 94.3 (81.2–143.6) 148.8 (91.2–198)
Rrs (cmH2O.l-1.s) 11.5 (7.4–11.8) 9.7 (6.8–10.4) 8.7 (6.6–10.3) 8.7 (7.8–11.2) 11.2 (9.1–13.8) 11.7 (9.6–15.3) 17.2 (13.9–22.8)
PEEPest (cmH2O) 26.7 (25.2–27.7) 20.9 (119.6–20.8) 16.4 (15.4–17.2) 12.3 (12.1–12.6) 8.4 (7.8–8.7) 6.2 (5.88–6.6) 0.45 (0.07–2.2)
R2 0.975 (0.97–0.985) 0.975 (0.97–0.983) 0.979 (0.97–0.985) 0.98 (0.97–0.988) 0.98 (0.97–0.99) 0.982 (0.97–0.99) 0.99 (0.88–0.99)
  1. Data are presented as median (range). Ers, elastance of the respiratory system; PEEP, positive end-expiratory pressure; PEEPappl, applied PEEP; PEEPest, estimated PEEP; Ppeak, peak ventilator pressure; Pplateau, plateau ventilator pressure; Rrs, resistance of the respiratory system; R2, coefficient of determination of the regression analysis.