Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hocanalysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial

Table 1 Patient characteristics: baseline parameters

	Placebo (n = 13)	rFVIIa (n = 17)
Female, number (percentage)	5 (38)	7 (41)
Age, years	32.6 ± 16.8	33.5 ± 13.7
Injury Severity Score	36.8 ± 12.8	38.7 ± 13.7
Abbreviated Injury Score head (region 1)	3 [3-5]	3 [3-5]
Mean arterial pressure, mm Hg	76 ± 22	71 ± 18 (n = 16)
Body temperature, °C	35.1 ± 1.3 (n = 8)	34.3 ± 1.8 (n = 9)
pH	7.24 ± 0.12 (n = 11)	7.22 ± 0.10 (n = 15)

Baseline refers to predosing. All data are presented as number of patients (percentage) or mean (± standard deviation shown in most cases) or median [minimum-maximum shown], and n is indicated in cases in which there are missing values. rFVIIa, recombinant activated factor VII.

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