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Table 1 Concentration of aromatic acids in serum sepsis patients and subjects of comparison groups

From: Microbial metabolites in the blood of patients with sepsis

Aromatic acid (ng/ml)

Patients with sepsis (n = 12)

Volunteers (n = 16)

Patients before surgery (n = 36)

Patients with smooth recovery (n = 9)

Patients with pneumonia (n = 10)

p-Hydroxyphenylacetic acid

2,140 (631–3,516)

72 (62–93)***

114 (53–220)***

263 (109–313)**

456 (344–667)*

3-Phenylpropionic acid

0

35 (20–54)**

4 (0–29)

0

0 (0–3)

Phenyllactic acid

367 (217–1,098)

47 (37–64)**

58 (37–93)**

89 (68–126)*

112 (89–177)*

p-Hydroxyphenyllactic acid

1,543 (564–2,731)

195 (159–371)***

254 (134–373)***

288 (269–772)*

465 (314–836)

1-Indolacetic acid

0

262 (113–385)***

47 (0–218)*

275 (228–499)***

0 (0–27)

3-Indolacetic acid

246 (183–628)

93 (56–141)*

181 (60–542)

57(30–74)*

231 (149–375)

  1. Data presented as median (25th–75th percentile range). *P < 0.05, **P < 0.001, ***P < 0.0001, compared with sepsis patients.