Table 1 Arterial blood gas variables, haemoglobin, and lactate
From: Vasopressin improves survival in a porcine model of abdominal vascular injury
Parameter | Group | Baseline | Haemorrhagic shock | Experimental therapy | Surgical intervention | ||
|---|---|---|---|---|---|---|---|
5 min after DA | 30 min after DA | 15 min | 60 min | ||||
7.34 ± 0.12 | 7.18 ± 0.10 | 7.08 ± 0.12 | 7.21 ± 0.13 | ||||
Fluid resuscitation | 7.50 ± 0.05 | 7.36 ± 0.08 | 7.17 ± 0.03 | - | - | - | |
Saline placebo | 7.52 ± 0.01 | 7.44 ± 0.08 | 7.41 ± 0.06 | - | - | - | |
Paco2 (mmHg) | Vasopressin | 37 ± 3 | 31 ± 4 | 30 ± 3 | 34 ± 5 | 44 ± 4 | 41 ± 5 |
Fluid resuscitation | 37 ± 3 | 30 ± 5 | 45 ± 7 | - | - | - | |
Saline placebo | 34 ± 3 | 24 ± 4* | 24 ± 7 | - | - | - | |
Pao2 (mmHg) | Vasopressin | 154 ± 19 | 132 ± 21 | 312 ± 134 | 437 ± 31 | 363 ± 102 | 262 ± 98 |
Fluid resuscitation | 138 ± 20 | 123 ± 28 | 300 ± 168 | - | - | - | |
Saline placebo | 154 ± 10 | 116 ± 25 | 239 ± 131 | - | - | - | |
Base excess (mmol/l) | Vasopressin | 5.7 ± 1.7 | -9.0 ± 4.5 | -8.8 ± 5.8 | -14.1 ± 6.1 | -15.2 ± 5.0 | -10.5 ± 6.0 |
Fluid resuscitation | 5.3 ± 3.8 | -7.7 ± 3.1 | -11.4 ± 1.4 | - | - | - | |
Saline placebo | 4.5 ± 1.8 | -7.5 ± 3.4 | -8.9 ± 3.3 | - | - | - | |
Haemoglobin (g/dl) | Vasopressin | 9.0 ± 1.2 | 7.7 ± 0.9 | 7.2 ± 1.0 | 6.4 ± 1.3 | 4.2 ± 0.7 | 3.3 ± 1.1 |
Fluid resuscitation | 8.5 ± 0.9 | 7.2 ± 1.5 | 4.4 ± 1.4 | - | - | - | |
Saline placebo | 8.4 ± 0.9 | 8.1 ± 0.5 | 7.8 ± 0.7 | - | - | - | |
Lactate (mmol/l) | Vasopressin | 1.78 ± 0.33 | 9.88 ± 2.78 | 11.10 ± 3.11 | 13.10 ± 3.44 | 11.55 ± 3.89 | 9.88 ± 3.55 |
Fluid resuscitation | 2.00 ± 1.22 | 7.55 ± 2.55 | 7.33 ± 2.66 | - | - | - | |
Saline placebo | 1.22 ± 0.22 | 5.99 ± 1.44* | 8.44 ± 2.66 | - | - | - | |