| Before intervention | n | After intervention | n | P value |
---|---|---|---|---|---|
Morphine | Â | Â | Â | Â | Â |
   Day 1 | 14 (61) | 23 | 24 (63) | 38 | 0.86 |
   Day 7 | 4 (36) | 11 | 11 (55) | 20 | 032 |
   Day 14 | 4 (57) | 7 | 4 (50) | 8 | 0.78 |
   Day 21 | 2 (67) | 3 | 1 (20) | 5 | 0.19 |
   Day 28 | 1 (50) | 2 | 2 (67) | 3 | 0.71 |
Midazolam | Â | Â | Â | Â | Â |
   Day 1 | 11 (48) | 23 | 16 (42) | 38 | 0.61 |
   Day 7 | 2 (18) | 11 | 5 (25) | 20 | 0.66 |
   Day 14 | 2 (29) | 7 | 3 (38) | 8 | 0.71 |
   Day 21 | 1 (33) | 3 | 1 (20) | 5 | 0.67 |
   Day 28 | 1 (50) | 2 | 2 (67) | 3 | 0.71 |
Propofol | Â | Â | Â | Â | Â |
   Day 1 | 10 (43) | 23 | 14 (38) | 38 | 0.66 |
   Day 7 | 3 (27) | 11 | 7 (35) | 20 | 0.66 |
   Day 14 | 2 (29) | 7 | 3 (38) | 8 | 0.88 |
   Day 21 | 1 (33) | 3 | 1 (20) | 5 | 0.67 |
   Day 28 | 1 (50) | 2 | 1 (33) | 3 | 0.71 |