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Table 2 Respiratory variables for the whole period of 29 days

From: Mechanical ventilation with lower tidal volumes does not influence the prescription of opioids or sedatives

 

Before intervention (n = 23)

After intervention (n = 38)

P value

 

Non-ALI/ARDS (n = 13)

ALI/ARDS (n = 10)

Non-ALI/ARDS (n = 23)

ALI/ARDS (n = 15)

 

VT (ml/kg PBW)

10.2 (9.3 to 11.1)

9.7 (8.9 to 10.5)

8.6 (7.8 to 9.5)

7.8 (7.2 to 8.5)

<0.001

Pmax (cmH2O)

18.2 (13.0 to 23.4)

21.8 (18.1 to 25.5)

16.8 (11.4 to 22.2)

25.6 (22.8 to 28.5)

0.01

RR (breaths/min)

21.3 (18.4 to 24.3)

18.3 (16.1 to 20.6)

23.4 (20.5 to 26.4)

25.6 (23.7 to 27.6)

<0.001

PaCO2 (kPa)

5.0 (4.3 to 5.7)

5.3 (4.8 to 5.8)

5.5 (4.9 to 6.2)

6.2 (5.8 to 6.6)

0.007

  1. P values were determined using linear mixed model analysis, comparing all four groups. Values are expressed as mean (95% confidence interval). ALI, acute lung injury; ARDS, acute respiratory distress syndrome; PaCO2, partial pressure of arterial carbon dioxide; Pmax, maximum airway pressure; RR, respiratory rate; VT, tidal volume.