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Table 1 Demographic variables

From: Mechanical ventilation with lower tidal volumes does not influence the prescription of opioids or sedatives

 

Before intervention (n = 23)

After intervention (n = 38)

P value

 

Non-ALI/ARDS (n = 13)

ALI/ARDS (n = 10)

Non-ALI/ARDS (n = 23)

ALI/ARDS (n = 15)

 

Male (n [%])

9 (69)

4 (40)

14 (61)

9 (60)

0.55

ABW (kg; median [IQR])

70.0 (70.0 to 75.0)

75.0 (61.5 to 97.0)

76.0 (70.0 to 95.0)

70.0 (60.0 to 80.0)

0.25

PBW (kg; median [IQR])

64.2 (52.4 to 70.6)

57.5 (52.6 to 70.1)

69.7 (59.7 to 75.1)

66.9 (57.9 to 75.1)

0.19

APACHE II (mean ± SD)

20.2 ± 7.5

22.8 ± 11.3

21.8 ± 7.1

19.9 ± 6.4

0.76

MVa (days; median [IQR])

4.0 (3.0 to 11.5)

13.5 (6.5 to 26.0)

5.0 (2.0 to 8.0)

13.0 (5.0 to 22.0)

0.004

ICU death (n [%])

2 (15)

7 (70)

3 (13)

4 (27)

0.005

PaO2/FiO2 ratiob (median [IQR])

225 (194 to 264)

138 (120 to 157)

216 (173 to 268)

146 (100 to 187)

< 0.001

Admission diagnosis (n (%])

     

   Medical

2 (15.4)

1 (10)

2 (8.7)

7 (46.7)

 

   Surgical

2 (15.4)

2 (20)

5 (21.7)

4 (26.7)

 

   Neurology/neurosurgery

5 (38.5)

2 (20)

6 (26.1)

2 (13.3)

 

   Cardiopulmonary surgery

2 (15.4)

3 (30)

3 (13.0)

2 (13.3)

 

   Cardiology

2 (15.4)

2 (20)

6 (26.1)

0

 
  1. P values were determined using χ2 test or one-way analysis of variance, comparing all four groups. aTotal number of mechanical ventilation (MV) days during the study period. bOn admission. ABW, actual body weight; ALI, acute lung injury; APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; PBW, predicted body weight.