Effects of high doses of selenium, as sodium selenite, in septic shock: a placebo-controlled, randomized, double-blind, phase II study

Table 4 Incidence and type of serious adverse events

Variable	Placebo group (n = 29)	Selenium group (n = 31)	P value
At least one serious adverse event	18 (62)	25 (81)	0.111
Type of event
Respiratory failure	1 (3)	5 (16)	0.196
Cardiac failure	1 (3)	1 (3)	1.000
Renal failure	1 (3)	0 (0)	0.483
Ischaemic event	6 (21)	2 (7)	0.134
Intracranial haemorrhage	1 (3)	1 (3)	1.000
Refractory shock	6 (21)	5 (16)	0.648
Multiorgan failure	4 (14)	10 (32)	0.091
Superinfection	2 (7)	1 (3)	0.606
Others^a	0 (0)	2 (7)	0.492

Data presented as n (%). ^aIncludes one thrombocytopenia and one radial artery pseudoaneurysm.

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