Table 5 Models fitted

Fixed effects

Initial status

Intercept (γ₀₀)

3.488***

3.631***

3.215***

2.327***

1.830***

Main effect

SEP (γ₀₁)

***

***

   SSM

1.029

1.402

   SPT

1.415

1.762

   NIN

0

0

DG (γ₀₂)

*

   Surgical

0.661

   Nonsurgical

0

Rate of change

TIME (γ₁₀)

-0.039^NS

0.438***

0.483***

0.471***

TIME*TIME (γ₂₀)

-0.077***

-0.079***

-0.078***

Factorial

SEP*TIME (γ₁₁)

*

*

   SSM

0.101

0.109

   SPT

-0.113

-0.104

   NIN

0

0

DG*TIME

NS/EX

SEP*DG

NS/EX

SEP*DG*TIME

NS/EX

Random effects (variance components)

Level 1

Residuals (var(e _ij ) = σ²)

1.001***

0.044***

0.265***

0.263***

0.263***

Level 2

Intercept (var(u_0i) = σ₀₀)

1.257***

2.069***

2.579***

2.045***

2.086***

TIME (var(u_1i) = σ₁₁)

0.078***

0.541***

0.534***

0.532***

TIME*TIME (var(u_2i)=σ₂₂)

0.008***

0.008***

0.008***

Akaike's information criteria

1,875.8

1,769.8

1,566.4

1,544.0

1,539.6

Schwarz's information criteria

1,883.5

1,785.4

1,592.4

1,580.4

1,578.6