Parameter | Increase ≥250 nmol/l (n = 170) | Increase <250 nmol/l (n = 235) | P | Peak ≥500 nmol/l (n = 276) | Peak <500 nmol/l (n = 129) | P |
---|---|---|---|---|---|---|
Baseline cortisol (nmol/l) | 323 (40–1160) | 375 (30–1870) | 0.014 | 435 (49–1870) | 220 (30–475) | < 0.0001 |
Baseline cortisol/albumin (nmol/g) | 21.6 (2–66) | 29.0 (1–198) | < 0.0001 | 28.6 (2–198) | 16.5 (1–62) | < 0.0001 |
t = 30 cortisol (nmol/l) | 635 (255–1740) | 475 (30–1910) | < 0.0001 | 640 (290–1910) | 350 (30–485) | < 0.0001 |
t = 60 cortisol (nmol/l) | 710 (335–1720) | 510 (30–1950) | < 0.0001 | 690 (350–1950) | 375 (30–495) | < 0.0001 |
Peak cortisol (nmol/l) | 710 (335–1740) | 520 (30–1950) | < 0.0001 | 695 (500–1950) | 385 (30–495) | < 0.0001 |
Peak <500 nmol/l | 20 (12) | 109 (46) | < 0.0001 | na | na | |
Cortisol increase (nmol/l) | 358 (250–1015) | 130 (-180–245) | < 0.0001 | 268 (-180–1015) | 135 (-100–373) | < 0.0001 |
Cortisol increase/albumin (nmol/g) | 21.7 (8–54) | 8.0 (-8–43) | < 0.0001 | 17.1 (-8–54) | 9.7 (-8–43) | < 0.0001 |
Cortisol increase <250 nmol/l | na | na | 126 (46) | 109 (84) | < 0.0001 |