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Table 2 Results of the adrenocorticotrophic hormone test

From: Predicting a low cortisol response to adrenocorticotrophic hormone in the critically ill: a retrospective cohort study

Parameter

Increase ≥250 nmol/l

(n = 170)

Increase <250 nmol/l

(n = 235)

P

Peak ≥500 nmol/l

(n = 276)

Peak <500 nmol/l

(n = 129)

P

Baseline cortisol (nmol/l)

323 (40–1160)

375 (30–1870)

0.014

435 (49–1870)

220 (30–475)

< 0.0001

Baseline cortisol/albumin (nmol/g)

21.6 (2–66)

29.0 (1–198)

< 0.0001

28.6 (2–198)

16.5 (1–62)

< 0.0001

t = 30 cortisol (nmol/l)

635 (255–1740)

475 (30–1910)

< 0.0001

640 (290–1910)

350 (30–485)

< 0.0001

t = 60 cortisol (nmol/l)

710 (335–1720)

510 (30–1950)

< 0.0001

690 (350–1950)

375 (30–495)

< 0.0001

Peak cortisol (nmol/l)

710 (335–1740)

520 (30–1950)

< 0.0001

695 (500–1950)

385 (30–495)

< 0.0001

Peak <500 nmol/l

20 (12)

109 (46)

< 0.0001

na

na

 

Cortisol increase (nmol/l)

358 (250–1015)

130 (-180–245)

< 0.0001

268 (-180–1015)

135 (-100–373)

< 0.0001

Cortisol increase/albumin (nmol/g)

21.7 (8–54)

8.0 (-8–43)

< 0.0001

17.1 (-8–54)

9.7 (-8–43)

< 0.0001

Cortisol increase <250 nmol/l

na

na

126 (46)

109 (84)

< 0.0001

 
  1. Values are expressed as median (range) or number (%), where appropriate. Exact P values are given where P < 0.10 500 nmol/l = 18 μg/dl cortisol. na, not applicable.