Skip to main content

Table 3 Comparison of patients with or without bacterial/parasitic infection (univariate analysis) and identification of variables predictive of bacterial/parasitic infection after stepwise logistic regression analysis (multivariate analysis)

From: Serum procalcitonin measurement as diagnostic and prognostic marker in febrile adult patients presenting to the emergency department

Variable Univariate analysis Multivariate analysis
  Nonbacterial/parasitic (n = 76) Bacterial/parasitic (n = 167) P Odds ratio [95% CI] P
Sex (male) 40 (47%) 94 (44%) NS   
Age (year) 54 ± 25 57 ± 19 NS   
Temperature (°C) 39.1 ± 0.6 39.2 ± 0.6 NS   
Heart rate (beats/min) 101 ± 21 107 ± 20 0.03   
Systolic arterial blood pressure (mmHg) 131 ± 23 127 ± 22 NS   
Immunodepression 20 (26%) 51 (30%) NS   
Headache 27 (35%) 37 (22%) 0.04   
Myalgia 23 (30%) 30 (18%) 0.04   
Emergency physician diagnosis 70 (29%) 173 (71%) < 0.001 7.54 [3.60–15.82] < 0.001
Haemoglobin level (mg/l) 128 ± 19 125 ± 23 NS   
White blood cell count (/mm3) 8060 ± 3777 11688 ± 8039 < 0.001   
Neutrophil leukocytes ≥ 7,500/mm3 21 (28%) 88 (54%) < 0.001 3.17 [1.52–6.62] 0.002
Platelet count (103/mm3) 198 ± 90 204 ± 99 NS   
Creatinine (μmol/l) 97 ± 39 118 ± 97 NS   
PCT (μg/l) 0.7 ± 2.2 11.1 ± 39.0 < 0.001   
PCT ≥ 0.2 μg/l 31 (41%) 128 (77%) < 0.001 4.54 [2.19–9.39] < 0.001
CRP (mg/l) 39 ± 48 150 ± 128 < 0.001   
CRP ≥ 40 mg/l 28 (38%) 122 (76%) < 0.001 3.67 [1.79–7.53] < 0.001
  1. Data are expressed as mean ± standard deviation or number (%). For multivariate analysis all other P values were NS. CI, confidence interval; CRP, C-reactive protein; NS, not significant; PCT, procalcitonin.