Skip to main content

Table 4 Diagnostic efficiency values for serum creatinine, cystatin C, and beta2-microglobulin to detect early renal dysfunction

From: Cystatin C and beta2-microglobulin: markers of glomerular filtration in critically ill children

 

Serum creatinine

Cystatin C

Beta2-microglobulin

Cutoff value

0.4 mg/dl

0.6 mg/l

1.5 mg/l

Sensitivity

42% (39%–46%)

85% (82%–89%)

85% (82%–89%)

Specificity

54% (49%–59%)

63% (58%–68%)

54% (49%–59%)

Positive likelihood ratio

0.94 (0.94–0.95)

2.3 (2.3–2.3)

1.8 (1.8–1.8)

  1. Sensitivity, specificity, and positive likelihood ratio (95% confidence interval) for serum creatinine, cystatin C, and beta2-microglobulin to diagnose renal dysfunction (creatinine clearance less than 80 ml/minute per 1.73 m2) are shown.