Table 1 Baseline and day 3 characteristics of patients in the derivation cohort
From: Prediction of death and prolonged mechanical ventilation in acute lung injury
Characteristic | Alive and not ventilator dependent by day 15 | Dead, ventilator-dependent, or with tracheostomy by day 15 | P |
|---|---|---|---|
Age | 53 (40 to 66) | 63 (49 to 72) | 0.004 |
Female sex (n [%]) | 34 (46) | 87 (34) | 0.063 |
BMI (kg/m2) | 27 (24 to 31) | 26 (23 to 31) | 0.138 |
SAPS II score | 46 (37 to 58) | 47 (35 to 59) | 0.760 |
Sepsis (n [%]) | 28 (38%) | 99 (39%) | 0.897 |
Extrapulmonary cause of ALI/ARDS (n [%]) | 29 (27%) | 45 (20%) | 0.205 |
Day 3 PaCO2 (mmHg) | 39 (33 to 44) | 41 (36 to 47) | 0.012 |
Day 3 PaO2/FiO2 | 174 (146 to 195) | 153 (105 to 198) | 0.013 |
Day 3 Vt (ml/kg PBW) | 9.1 (7.2 to 10.6) | 8.5 (7.1 to 10.4) | 0.181 |
Day 3 Ppl (cmH2O) | 23 (19 to 26) | 26 (21 to 30) | 0.012 |
Day 3 Ppk (cmH2O) | 28 (26 to 32) | 31 (27 to 38) | 0.010 |
Day 3 PEEP (cmH2O) | 5 (5 to 9) | 8 (5 to 12) | 0.003 |
Day 3 VE40 (ml/kg PBW/min) | 142 (109 to 186) | 162 (128 to 214) | 0.006 |
Day 3 oxygenation index | 10.4 (8.2 to 14.7) | 13.9 (9.3 to 23.1) | 0.001 |
Day 3 ΔPEEP (cmH2O)a | 0 (-2 to 0) | 0 (0 to 3) | < 0.001 |
Day 3 SOFA score | 9 (7 to 10) | 10 (7 to 13) | 0.055 |
Day 3 shock (n [%]) | 14 (19) | 99 (39) | 0.001 |