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Table 4 Plasma cytokine concentrations: survivors versus nonsurvivors

From: Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis

Cytokines Survivors (n = 31) Nonsurvivors (28-day mortality; n = 29) P valuea
IL-1β 0.39 (0.00–3.04) 1.30 (0.22–7.21) 0.050
IL-2 2.80 (0.00–8.10) 3.01 (0.00–7.21) 0.982
IL-4 0.00 (0.00–0.03) 0.84 (0.00–26.28) 0.042
IL-5 1.76 (0.08–6.19) 0.47 (0.00–2.28) 0.067
IL-6 1,957.77 (971.92–6,295.47) 6,254.96 (2,446.01–15,972.40) 0.014
IL-7 1.30 (0.00–14.14) 7.61 (0.60–10.96) 0.297
IL-8 94.69 (20.94–138.35) 281.39 (83.99–773.51) 0.001
IL-10 9.70 (2.00–40.89) 26.92 (5.29–96.58) 0.137
IL-12 1.09 (0.00–40.89) 1.04 (0.00–6.79) 0.958
IL-13 4.69 (0.00–17.90) 3.13 (0.00–12.94) 0.804
IL-17 0.00 (0.00–0.00) 0.00 (0.00–0.20) 0.085
IFN-γ 12.34 (0.00–91.69) 28.71 (0.00–122.94) 0.492
G-CSF 116.00 (12.00–367.00) 423.61 (0.00–2,488.50) 0.336
GM-CSF 0.00 (0.00–21.68) 0.00 (0.00–140.97) 0.221
MIP-1 253.25 (127.49–365.95) 228.41 (140.80–617.30) 0.706
MCP-1 268.36 (0.00–759.30) 757.78 (324.61–1,966.88) 0.004
TNF-α 8.00 (0.00–25.72) 9.04 (2.31–43.28) 0.224
  1. Values are in pg/ml, and as expressed as mean (range). aMann-Whitney rank sum test. G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL, interleukin; IFN, interferon; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; TNF, tumour necrosis factor.