Table 4 Plasma cytokine concentrations: survivors versus nonsurvivors
From: Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis
Cytokines | Survivors (n = 31) | Nonsurvivors (28-day mortality; n = 29) | P valuea |
|---|---|---|---|
IL-1β | 0.39 (0.00–3.04) | 1.30 (0.22–7.21) | 0.050 |
IL-2 | 2.80 (0.00–8.10) | 3.01 (0.00–7.21) | 0.982 |
IL-4 | 0.00 (0.00–0.03) | 0.84 (0.00–26.28) | 0.042 |
IL-5 | 1.76 (0.08–6.19) | 0.47 (0.00–2.28) | 0.067 |
IL-6 | 1,957.77 (971.92–6,295.47) | 6,254.96 (2,446.01–15,972.40) | 0.014 |
IL-7 | 1.30 (0.00–14.14) | 7.61 (0.60–10.96) | 0.297 |
IL-8 | 94.69 (20.94–138.35) | 281.39 (83.99–773.51) | 0.001 |
IL-10 | 9.70 (2.00–40.89) | 26.92 (5.29–96.58) | 0.137 |
IL-12 | 1.09 (0.00–40.89) | 1.04 (0.00–6.79) | 0.958 |
IL-13 | 4.69 (0.00–17.90) | 3.13 (0.00–12.94) | 0.804 |
IL-17 | 0.00 (0.00–0.00) | 0.00 (0.00–0.20) | 0.085 |
IFN-γ | 12.34 (0.00–91.69) | 28.71 (0.00–122.94) | 0.492 |
G-CSF | 116.00 (12.00–367.00) | 423.61 (0.00–2,488.50) | 0.336 |
GM-CSF | 0.00 (0.00–21.68) | 0.00 (0.00–140.97) | 0.221 |
MIP-1 | 253.25 (127.49–365.95) | 228.41 (140.80–617.30) | 0.706 |
MCP-1 | 268.36 (0.00–759.30) | 757.78 (324.61–1,966.88) | 0.004 |
TNF-α | 8.00 (0.00–25.72) | 9.04 (2.31–43.28) | 0.224 |