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Table 2 Plasma cytokine concentrations: severe sepsis versus septic shock

From: Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis

Cytokine Severe sepsis (n = 14) Septic shock (n = 46) P valuea
IL-1β 0.17 (0.00–0.79) 1.22 (0.01–7.33) 0.01
Il-6 1027 (583.1–4854) 5632 (1889–12170) 0.007
IL-7 0.00 (0.00–0.00) 8.475 (0.60–13.56) < 0.001
IL-8 52.63 (24.16–122.4) 145.3 (74.37–520.2) 0.01
IL-10 2.270 (0.9500–11.72) 27.45 (6.835–116.3) < 0.001
IL-13 0.27 (0.00–4.61) 7.21 (0.03–19.29) 0.008
IFN-γ 0.0000 (0.00–22.77) 33.10 (0.00–116.7) 0.03
MCP-1 6.295 (0.00–372.2) 753.9 (324.6–1689) < 0.001
TNF-α 0.00 (0.00–2.78) 14.46 (2.68–47.00) < 0.001
  1. Values are in pg/ml, and as expressed as mean (range). aMann-Whitney rank sum test. IL, interleukin; IFN, interferon; MCP, monocyte chemoattractant protein; TNF, tumour necrosis factor.