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Table 2 Plasma cytokine concentrations: severe sepsis versus septic shock

From: Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis

Cytokine

Severe sepsis (n = 14)

Septic shock (n = 46)

P valuea

IL-1β

0.17 (0.00–0.79)

1.22 (0.01–7.33)

0.01

Il-6

1027 (583.1–4854)

5632 (1889–12170)

0.007

IL-7

0.00 (0.00–0.00)

8.475 (0.60–13.56)

< 0.001

IL-8

52.63 (24.16–122.4)

145.3 (74.37–520.2)

0.01

IL-10

2.270 (0.9500–11.72)

27.45 (6.835–116.3)

< 0.001

IL-13

0.27 (0.00–4.61)

7.21 (0.03–19.29)

0.008

IFN-γ

0.0000 (0.00–22.77)

33.10 (0.00–116.7)

0.03

MCP-1

6.295 (0.00–372.2)

753.9 (324.6–1689)

< 0.001

TNF-α

0.00 (0.00–2.78)

14.46 (2.68–47.00)

< 0.001

  1. Values are in pg/ml, and as expressed as mean (range). aMann-Whitney rank sum test. IL, interleukin; IFN, interferon; MCP, monocyte chemoattractant protein; TNF, tumour necrosis factor.