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Table 1 Characteristics of included studies: parallel-design studies

From: Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review

Study Year Country of origin Randomization Conventional therapy PMX-F
     N Percentage of males APACHE II score Predicted mortality (percentage) N Percentage of males APACHE II score Predicted mortality (percentage)
Tani et al. [21] (a)a 1998 Japan No 33 69.7 SSS 39.1 N/A 37 78.4 SSS 46.2 N/A
Nakamura et al. [10] 1999 Japan Yes 20 60.0 NS N/A 30 60.0 24.8 52.6
Nemoto et al. [14] 2001 Japan Yes 44 61.4 23 46.0 54 64.7 22 42.4
Nakamura et al. [11] (a) 2002 Japan Yes 9 66.7 27.5 62.2 9 66.7 28.5 65.6
Suzuki et al. [15] 2002 Japan Yes 24 70.8 25 53.3 24 75.0 25 53.3
Tsushima et al. [33] 2002 Japan No 10 80.0 NS N/A 24 70.8 22.4 43.9
Tsugawa et al. [31] 2002 Japan No 51 43.1 NS N/A 31 45.2 NS N/A
Nakamura et al. [8] (b) 2003 Japan Yes 10 60.0 27 60.5 10 60.0 27.6 62.5
Nakamura et al. [12] (c) 2003 Japan Yes 25 64.0 23 46.4 35 68.6 24.2 50.4
Nakamura et al. [29] (d) 2003 Japan No 108 62.0 24 49.7 206 64.1 24.6 51.9
Nakamura et al. [13] (e) 2004 Japan Yes 10 60.0 28 63.9 15 60.0 28.4 65.2
Nakamura et al. [9] (f) 2004 Japan Yes 50 64.0 24.8 52.6 70 61.4 25.4 54.8
Ono et al. [30] 2004 Japan No 13 61.5 8.8 9.7 10 60.0 19.6 34.2
Tsujimoto et al. [32] 2004 Japan No 10 20.0 10.6 12.2 7 85.7 19.4 33.5
Nakamura et al. [19] (g) 2005 Japan No 12 58.3 25 53.3 14 64.3 25.5 55.1
Vincent et al. [28] 2005 Belgium, UK, Germany, Netherlands, Spain Yes 18 47.4 18.7 31.3 17 76.5 16.7 25.4
Total     447     593    
  1. aTwo studies reported severity of illness as SSS rather than APACHE score.
  2. APACHE II score expressed as the mean. Predicted mortality was calculated as eLogit/(1+ eLogit), where Logit = -3.517 + (APACHE II) × 0.146. APACHE, Acute Physiology and Chronic Health Evaluation; N/A, not applicable; NS, not stated; PMX-F, polymyxin B-immobilized fiber column; SSS, Sepsis Severity Score.