Acute renal failure in patients with sepsis

Table 1 Baseline characteristics

Variable	No AKI	Risk	Injury	Failure	P
n	114	11	21	36
Age (years)^a	54 ± 18.2	61.9 ± 20.9	61.6 ± 13.4	61.8 ± 16.3	NS
Sex (male)	65 (57)	10 (91)	18 (85.7)	27 (75)	0.009
Race (Caucasian)	102 (89.5)	10 (91)	20 (95.2)	30 (83.3)	NS
Severe sepsis^b	77 (67.5)	6 (54.5)	12 (57.1)	13 (36.1)	0.012
Septic shock^b	25 (21.9)	4 (36.4)	8 (38)	23 (64)	<0.0001
CVD	37 (32.4)	3 (27.3)	10 (47.6)	14 (38.9)	NS
CKD	5 (43.9)	1 (9)	4 (19)	8 (22.2)	0.009
SAPS II > 50	22 (19.3)	6 (54.5)	7 (33.3)	9 (26.5)	0.06
Mortality	11 (9.6)	3 (27.3)	6 (28.6)	20 (55)	<0.0001

Figures in parentheses are percentages. AKI, acute kidney injury; CKD, chronic kidney disease; CVD, cardiovascular disease, diabetes mellitus and hypertension; NS, not significant; SAPS II, Simplified Acute Physiology Score, version II. The SAPS II was calculated on the basis of the worst variables recorded during the first 24 hours of ICU admission. ^aMeans ± SD; ^bsepsis was classified in accordance with American College of Chest Physicians and the Society of Critical Care Medicine consensus [2].

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