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Table 1 Clinical features frequently associated with alveolar hypoventilation

From: Clinical review: Long-term noninvasive ventilation

Shortness of breath during activities of daily living in the absence of paralysis
Orthopnea in patients with disordered diaphragmatic dysfunction
Poor sleep quality: insomnia, nightmares and frequent arousals
Nocturnal or early morning headaches
Daytime fatigue, drowsiness and sleepiness, loss of energy
Decrease in intellectual performance
Loss of appetite and weight loss
Appearance of recurrent complications: respiratory infections
Clinical signs of cor pulmonale