|1.||Epidemiology of AKI||
What is a 'nomenclature' that is based on simple, universally available data and that can identify all patients globally with AKI irrespective of location and age?|
What are the data to help determine etiology once AKI is identified?
What are the correlates of AKI in regard to pathology/physiology?
Is there a validated method for assessing severity of AKI separate from multiple organ failure?
What is the relationship between degree of severity and outcomes?
|2.||Outcomes from AKI||What are the clinically meaningful outcomes that are important in clinical studies of AKI?|
|3.||Strategies to change outcomes||
|Timing of initiation|
|Modality selection (CRRT, IHD, PD)|
|Intensity of therapy (dose)|
|Cessation of renal replacement therapy|
|4.||Data needed to advance knowledge in AKI||
Datasets collected at contact with health care system|
Intensive care unit admission
Biological sample repositories
|5||Process outcomes||Measures of effectiveness of current processes for changing behavior/attitude of caregivers and ultimately patient outcomes from AKI.|