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Figure 5 | Critical Care

Figure 5

From: Hyperoxia increases ventilator-induced lung injury via mitogen-activated protein kinases: a prospective, controlled animal experiment

Figure 5

Effects of hyperoxia on stretch-induced JNK activation of airway epithelium in JNK knockout mice. Phospho-JNK-positive cells were quantified as the average number of epithelial cells with dark brown DAB signals per bronchiole, which were counted from 10 randomly chosen bronchioles of each section (n = 5 per group). *p < 0.05 versus control, non-ventilated mice; †p < 0.05 versus all other groups. DAB, diaminobenzidine; JNK, c-Jun NH2-terminal kinase; RA, room air; VT, tidal volume; WT, wild-type mice.

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