Table 1 Drugs having 'membrane stabilising activity' with the potential for severe cardiotoxicity depending on dose
From: Clinical review: Aggressive management and extracorporeal support for drug-induced cardiotoxicity
Anti-arrhythmics class I Vaughan Williams | Flecainide, disopyramide, cibenzoline, propafenone, quinidine, lidocaine, procainamide |
Beta-blockers | Propranolol, acebutolol, nadoxolol, pindolol, penbutolol, labetalol, oxprenolol |
Polycyclic antidepressants | Imipramine, desipramine, amitritptyline, clomipramine, dosulepin, doxepin, maprotiline |
Selective serotonin reuptake inhibitors | Include venlafaxine, citalopram |
Dopamine and norepinephrine uptake inhibitors | Include bupropion |
Anti-epileptics | Include carbamazepine, phenytoin |
Phenothiazines | Include thioridazine |
Opioids | Include dextropropoxyphene |
Antimalarial agents | Include chloroquine and quinine |
Anaesthetic-recreational agents | Include cocaine |