Table 6 Incidence of liver dysfunction
From: Liver dysfunction associated with artificial nutrition in critically ill patients
TPN | EN | Total | p | OR (95% CI) | |
|---|---|---|---|---|---|
Overall patients | 303 | 422 | 725 | ||
Liver dysfunction | 91 (30%) | 75 (18%) | 166 (23%) | 0.001 | 1.7 (1.3–2.2) |
Cholestasis | 31 (10%) | 25 (6%) | 56 (8%) | 0.03 | 1.7 (1.04–2.9) |
Hepatic necrosis | 28 (9%) | 20 (5%) | 48 (7%) | 0.02 | 1.95 (1.1–3.4) |
Mixed pattern | 56 (19%) | 43 (10%) | 99 (14%) | 0.001 | 1.8 (1.3–2.6) |
Acalculous cholecystitis | 1 | 2 | 3 | ||
Type of patients and liver dysfunction | 91 | 75 | 166 | ||
Medical | 24 (23%) | 44 (17%) | 68 (19%) | 0.3 | 1.2 (0.8–1.7) |
Surgical | 55 (31%) | 14 (16%) | 69 (26%) | 0.03 | 1.8 (1.02–3.1) |
Trauma | 12 (52%) | 17 (23%) | 29 (37%) | 0.02 | 2.1 (1.1–4) |
Septic patients | 122 | 86 | 208 | ||
Liver dysfunction | 47 (39%) | 21 (24%) | 68 (33%) | 0.03 | 1.6 (1.02–2.4) |
Cholestasis | 17 (14%) | 6 (7%) | 23 (11%) | 0.1 | 1.9 (0.8–4.9) |
Hepatic necrosis | 10 (8%) | 3 (4%) | 13 (6%) | 0.2 | 2.4 (0.7–8.2) |
Mixed pattern | 30 (25%) | 14 (16%) | 44 (21%) | 0.1 | 1.5 (0.9–2.7) |
Non-septic patients | 181 | 336 | 517 | ||
Liver dysfunction | 44 (24%) | 54 (16%) | 98 (19%) | 0.02 | 1.5 (1.06–2.2) |
Cholestasis | 14 (8%) | 19 (6%) | 33 (6%) | 0.4 | 1.4 (0.7–2.7) |
Hepatic necrosis | 18 (10%) | 17 (5%) | 35 (7%) | 0.04 | 2 (1.03–3.7) |
Mixed pattern | 26 (14%) | 29 (9%) | 55 (11%) | 0.04 | 1.7 (1.01–2.7) |