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Table 6 Incidence of liver dysfunction

From: Liver dysfunction associated with artificial nutrition in critically ill patients

  TPN EN Total p OR (95% CI)
Overall patients 303 422 725   
   Liver dysfunction 91 (30%) 75 (18%) 166 (23%) 0.001 1.7 (1.3–2.2)
   Cholestasis 31 (10%) 25 (6%) 56 (8%) 0.03 1.7 (1.04–2.9)
   Hepatic necrosis 28 (9%) 20 (5%) 48 (7%) 0.02 1.95 (1.1–3.4)
   Mixed pattern 56 (19%) 43 (10%) 99 (14%) 0.001 1.8 (1.3–2.6)
   Acalculous cholecystitis 1 2 3   
Type of patients and liver dysfunction 91 75 166   
   Medical 24 (23%) 44 (17%) 68 (19%) 0.3 1.2 (0.8–1.7)
   Surgical 55 (31%) 14 (16%) 69 (26%) 0.03 1.8 (1.02–3.1)
   Trauma 12 (52%) 17 (23%) 29 (37%) 0.02 2.1 (1.1–4)
Septic patients 122 86 208   
   Liver dysfunction 47 (39%) 21 (24%) 68 (33%) 0.03 1.6 (1.02–2.4)
   Cholestasis 17 (14%) 6 (7%) 23 (11%) 0.1 1.9 (0.8–4.9)
   Hepatic necrosis 10 (8%) 3 (4%) 13 (6%) 0.2 2.4 (0.7–8.2)
   Mixed pattern 30 (25%) 14 (16%) 44 (21%) 0.1 1.5 (0.9–2.7)
Non-septic patients 181 336 517   
   Liver dysfunction 44 (24%) 54 (16%) 98 (19%) 0.02 1.5 (1.06–2.2)
   Cholestasis 14 (8%) 19 (6%) 33 (6%) 0.4 1.4 (0.7–2.7)
   Hepatic necrosis 18 (10%) 17 (5%) 35 (7%) 0.04 2 (1.03–3.7)
   Mixed pattern 26 (14%) 29 (9%) 55 (11%) 0.04 1.7 (1.01–2.7)
  1. CI, confidence interval; EN, enteral nutrition; OR, odds ratio; TPN, total parenteral nutrition.