From: Liver dysfunction associated with artificial nutrition in critically ill patients
With liver dysfunction | Without liver dysfunction | Total | p | |
---|---|---|---|---|
Number of patients | 166 (23%) | 559 (77%) | 725 | |
Women | 54 (33%) | 183 (33%) | 237 (33%) | 0.9 |
Age in years | 63 (47–72) | 63 (44–73) | 63 (47–72) | 0.8 |
APACHE II score | 18 (14–23) | 18 (12–22) | 18 (12–22) | 0.2 |
MODS | 6 (4–8) | 5 (3–7) | 5 (3–7) | 0.001 |
Primary diagnosis | 0.4 | |||
Gastrointestinal surgery | 52 | 126 | 178 | |
Respiratory failure | 26 | 107 | 133 | |
Stroke | 27 | 98 | 125 | |
Cardiovascular | 14 | 72 | 86 | |
Trauma | 16 | 67 | 83 | |
Infections in non-immunosuppressed patients | 12 | 28 | 40 | |
Infections in immunosuppressed patients | 3 | 8 | 11 | |
Metabolic diseases | 1 | 9 | 10 | |
Urology | 3 | 7 | 10 | |
Hematology | 1 | 8 | 9 | |
Poisoning | 2 | 6 | 8 | |
Obstetrics/Gynecology | 3 | 4 | 7 | |
AIDS | 1 | 1 | 2 | |
Other | 5 | 18 | 23 | |
Type of patients | 0.03 | |||
Medical | 68 | 294 | 362 | |
Surgical | 69 | 195 | 264 | |
Trauma | 29 | 70 | 99 | |
Sepsis on admission | 68 (41%) | 140 25%) | 208 (29%) | 0.001 |
Septic shock on admission | 33 (20%) | 72 (13%) | 105 (15%) | 0.02 |
Patients on mechanical ventilation | 152 (92%) | 469 (84%) | 621 (86%) | 0.01 |
Days of mechanical ventilation | 13 (6–24) | 7 (3–14) | 8 (3–16) | 0.001 |
Intensive care unit length of stay in days | 16 (8–28) | 9 (5–17) | 10 (6–20) | 0.001 |
Hospital length of stay in days | 28 (17–29) | 23 (14–28) | 25 (15–29) | 0.01 |
Mortality at 28 days | 47 (28.3%) | 157 (28.1%) | 204 (28%) | 0.9 |