Severe protein C deficiency association with organ dysfunction and mortality in patients with severe sepsis

Table 1 abstract p7

Study	EVAA			PROWESS			ENHANCE			ADDRESS
Protein C	≤ 40%	>40%		≤ 40%	>40%		≤ 40%	>40%		≤ 40%	>40%
n	65	60		615	959		795	1127		593	1154
Mean APACHE II score	17.4	17.1	P = 0.79	25.9	24.1	P < 0.001	23.2	20.9	P < 0.001	18.5	18.1	P = 0.14
Mean OD	1.5	1.4	P = 0.42	2.8	2.2	P < 0.001	3.1	2.4	P < 0.001	1.6	1.4	P < 0.001
Placebo mortality	50.0%	20.0%	P = 0.07	41.8%	25.3%	P < 0.001				19.7%	12.0%	P = 0.002

ISSN: 1364-8535