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Table 3 Changes in Doppler measurements during reactive hyperaemia according to sedation types

From: Microcirculatory alterations induced by sedation in intensive care patients. Effects of midazolam alone and in association with sufentanil

  NS period H period HS period
Φpeak (PU) 292 ± 31 304 ± 28 274 ± 25
ΔΦ (PU) 141 ± 14 97 ± 16a 73 ± 9a
TP (seconds) 23.5 ± 4.3 43.8 ± 11.5 24.2 ± 8.2
T1/2 R (seconds) 38.8 ± 13.7 22.9 ± 3.4 23.8 ± 5.5
TR (seconds) 170.1 ± 40.5 117.2 ± 3.4 85.1 ± 14.9
Slope 1 (PU/second) 53.6 ± 13.3 51.5 ± 8.8 74.1 ± 10.9a,b
Slope 2 (PU/second) 10.8 ± 3.7 8.2 ± 3.0 8.7 ± 0.7
  1. ap < 0.05 versus NS period; bp < 0.05 versus H period. ΔΦ, Φpeak - Φrest; Φpeak, maximal blood flow during reactive hyperaemia; H period, set of measurements obtained when the patients were sedated by midazolam; HS period, set of measurements obtained when the patients were sedated by midazolam and sufentanil; NS period, set of measurements obtained when the patients were non-sedated; PU, perfusion units; T1/2 R, time to half flow normalisation; TP, time to peak; TR, time to flow normalisation.