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Table 3 Changes in Doppler measurements during reactive hyperaemia according to sedation types

From: Microcirculatory alterations induced by sedation in intensive care patients. Effects of midazolam alone and in association with sufentanil

 

NS period

H period

HS period

Φpeak (PU)

292 ± 31

304 ± 28

274 ± 25

ΔΦ (PU)

141 ± 14

97 ± 16a

73 ± 9a

TP (seconds)

23.5 ± 4.3

43.8 ± 11.5

24.2 ± 8.2

T1/2 R (seconds)

38.8 ± 13.7

22.9 ± 3.4

23.8 ± 5.5

TR (seconds)

170.1 ± 40.5

117.2 ± 3.4

85.1 ± 14.9

Slope 1 (PU/second)

53.6 ± 13.3

51.5 ± 8.8

74.1 ± 10.9a,b

Slope 2 (PU/second)

10.8 ± 3.7

8.2 ± 3.0

8.7 ± 0.7

  1. ap < 0.05 versus NS period; bp < 0.05 versus H period. ΔΦ, Φpeak - Φrest; Φpeak, maximal blood flow during reactive hyperaemia; H period, set of measurements obtained when the patients were sedated by midazolam; HS period, set of measurements obtained when the patients were sedated by midazolam and sufentanil; NS period, set of measurements obtained when the patients were non-sedated; PU, perfusion units; T1/2 R, time to half flow normalisation; TP, time to peak; TR, time to flow normalisation.
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Critical Care

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