Effect of extracorporeal liver support by MARS and Prometheus on serum cytokines in acute-on-chronic liver failure

Table 1 Patient characteristics

Patient	Age (years)	Gender	Underlying disease	Precipitating event	Follow-up (days)	Cause of death	M	P	Creatinine (mg/dl)	INR	Bilirubin (mg/dl)	Albumin (g/dl)	MELD score^a	Child-Pugh score	SOFA score
1	53	Female	Cirrhosis, chronic HCV	SBP	6	Sepsis	2	2	1.0	3.15	16	3.0	30	12	14
2	55	Male	Alcoholic cirrhosis	Alcoholic hepatitis	30	Sepsis	2	2	2.3	3.10	39	2.8	41	12	15
3	61	Male	Metastatic colon cancer	Liver resection	3	Multi-organ failure	1	1	0.6	1.10	25	2.8	15	11	14
4	51	Male	Alcoholic cirrhosis	Bleeding	9	Multi-organ failure	2	2	2.5	2.13	33	2.9	37	13	12
5	65	Female	Alcoholic cirrhosis	Alcoholic hepatitis	106	Sepsis	4	4	1.8	1.96	37	2.9	33	12	13
6	60	Male	Alcoholic cirrhosis	Alcoholic hepatitis	Alive, OLT day 25	n/a	2	2	5.9	2.70	38	3.0	48	13	12
7	61	Male	OLT, graft dysfunction	n/a	625	Lung cancer	2	2	1.1	1.18	20	3.3	21	9	15
8	56	Female	Alcoholic cirrhosis	Alcoholic hepatitis	Alive	n/a	2	2	1.0	2.10	26	2.4	27	12	11

^aMELD score was obtained using the MELD calculator at the website of the Mayo Clinic (Rochester, MN, USA), http://www.mayoclinic.org/gi-rst/mayomodel5.html. HCV, hepatitis C virus; INR, international normalized ratio; M, MARS™ (molecular adsorbent recirculating system) sessions; MELD, model for end-stage liver disease; n/a, not applicable; OLT, orthotopic liver transplantation; P, Prometheus™ sessions; SBP, spontaneous bacterial peritonitis; SOFA, sepsis-related organ failure assessment.

ISSN: 1364-8535