Figure 2

Course of serum cytokine levels during the study. Levels of individual cytokines are shown at the beginning (before first treatment) and at the end (after last treatment) of the study period, which consisted of two to eight treatments (four treatments on average; Table 1). Results are presented separately for survivors (n = 4; open triangles, dashed lines) and non-survivors (n = 4; filled triangles, unbroken lines) at day 30. Values are expressed as median (Q1; Q3). Shaded areas indicate normal range. Cytokine levels were not different between survivors and non-survivors at any time point or between the beginning and the end of the study period in both survivors and non-survivors. IL, interleukin; sTNF-αR1, soluble tumor necrosis factor-alpha receptor 1; TNF-α, tumor necrosis factor-alpha.