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Table 2 Univariate and multivariable analyses for pre- and intraoperative factors associated with peak blood lactate value

From: Hyperlactatemia during cardiopulmonary bypass: determinants and impact on postoperative outcome

Univariate analysis (correlation matrix)
Factor Correlation coefficient p value
Age (years) -0.099 0.032
Ejection fraction -0.181 0.001
Congestive heart failure 0.191 0.001
Preoperative serum creatinine value (mg/dl) 0.191 0.001
Active endocarditis 0.177 0.001
Isolated coronary operation -0.094 0.041
CPB duration (minutes) 0.523 0.001
Lowest temperature (°C) on CPB -0.312 0.001
Lowest hematocrit on CPB -0.158 0.001
Lowest pump flow (l/minute per m2) on CPB -0.271 0.001
Lowest Do2 (ml/minute per m2) on CPB -0.276 0.001
Peak blood glucose (mg/dl) on CPB 0.517 0.001
Multivariable analysis (linear regression)
Factor B coefficient p value
Constant 0.326  
Preoperative serum creatinine value (mg/dl) 0.123 0.032
Active endocarditis 0.177 0.001
CPB duration (minutes) 0.012 0.001
Lowest Do2 (ml/minute per m2) on CPB -0.004 0.004
Peak blood glucose (mg/dl) on CPB 0.009 0.001
  1. CPB, cardiopulmonary bypass; Do2, oxygen delivery.