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Table 3 Course of coagulation parameters

From: Children undergoing cardiac surgery for complex cardiac defects show imbalance between pro- and anti-thrombotic activity

Coagulation parameter

TCPC group Mean ± SEM

BV repair group Mean ± SEM

Time point

PT (percentage)

PTT (seconds)

Fibrinogen (mg/dl)

AT III (percentage)

PT (percentage)

PTT (seconds)

Fibrinogen (mg/dl)

AT III (percentage)

Preoperative

92.3 ± 2.5

32.2 ± 1.0

2.8 ± 0.2

43.8 ± 12.6

89.0 ± 8.0

36.0 ± 1.7

3.0 ± 0.2

46.9 ± 13.7

4 hours postoperative

62.3 ± 3.9

47.7 ± 5.6

1.5 ± 0.1

20.4 ± 4.1

70.9 ± 3.4

37.8 ± 1.7

1.7 ± 0.3

27.4 ± 6.9

24 hours postoperative

51.4 ± 6.2

39.5 ± 35.9

1.9 ± 0.2a

20.9 ± 4.7

62.8 ± 4.7

33.9 ± 2.4

2.9 ± 0.4a

38.5 ± 13.4

72 hours postoperative

75.5 ± 6.7

45.3 ± 11.9

2.8 ± 0.3a

37.9 ± 14.2

84.0 ± 8.5

33.5 ± 1.9

4.1 ± 0.5a

48.2 ± 17.7

At discharge

47.0 ± 8.5a

37.0 ± 1.7a

nd

nd

95.3 ± 1.8a

31.3 ± 1.6a

nd

nd

  1. aSignificant difference (p ≤ 0.05) of values between the two groups. AT III, antithrombin III; BV, biventricular; nd, not diagnosed; PT, prothrombin time; PTT, partial thromboplastin time; SEM, standard error of the mean; TCPC, total cavopulmonary connection.