Neutrophil apoptosis: a marker of disease severity in sepsis and sepsis-induced acute respiratory distress syndrome

Fialkow, Léa; Fochesatto Filho, Luciano; Bozzetti, Mary C; Milani, Adriana R; Rodrigues Filho, Edison M; Ladniuk, Roberta M; Pierozan, Paula; de Moura, Rafaela M; Prolla, João C; Vachon, Eric; Downey, Gregory P

doi:10.1186/cc5090

Critical Care

Table 2 Detailed description of the medical patients

From: Neutrophil apoptosis: a marker of disease severity in sepsis and sepsis-induced acute respiratory distress syndrome

Patient	Group
Uncomplicated sepsis (n = 8)
	Diagnosis	Site of infection	Microorganism	Material
1	Pneumonia/COPD	Respiratory	Not identified	Sputum/Blood
2	Pneumonia/COPD	Respiratory	Staphylococcus aureus	Blood
3	Pneumonia/Stroke	Respiratory	Not identified	Sputum/Blood
4	Pneumonia/Guillain-Barre syndrome	Respiratory	Enterobacter sp	Sputum
5	Pneumonia/Subarachnoid hemorrhage	Respiratory	Staphylococcus sp	Blood
6	Pneumonia/DM/Pickwick syndrome	Respiratory	Not identified	Sputum/Blood
7	Pneumonia/Head trauma	Respiratory	Pseudomonas aeruginosa	Sputum
8	Pneumonia/Intracerebral hemorrhage	Respiratory	S. aureus	Sputum
Septic shock (n = 12)
	Diagnosis	Site of infection	Microorganism	Material
1	Pneumonia/COPD	Respiratory	S. aureus	Blood
2	Pneumonia	Respiratory	S. aureus	Sputum
3	Pneumonia/COPD	Respiratory	S. aureus	Blood
4	Pneumonia/COPD	Respiratory	P. aeruginosa/Haemophilus influenzae	Sputum
5	Pneumonia/UTI	Respiratory/Urinary	Not identified/Klebsiella pneumoniae	Sputum/Urine
6	Pneumonia/UTI/DM	Respiratory/Urinary	Not identified/Candida sp	Sputum/Blood and urine
7	UTI/SBP/Cirrhosis	Abdominal/Urinary	S. aureus and Streptococcus viridans/Enterococcus faecium, S. viridans, and Escherichia coli	Ascites/Urine
8	Pneumonia	Respiratory	Not identified	Sputum/Blood
9	Pneumonia/COPD	Respiratory	Not identified	Sputum/Blood
10	Meningitis	CNS	Neisseria meningitis	Liquor/Blood
11	UTI/Lyell syndrome	Urinary/Skin	Enterococcus sp/Acinetobacter sp	Urine/Skin secretion
12	Pneumonia	Respiratory	S. aureus	Blood
Sepsis-induced ARDS (n = 9)
	Diagnosis	Site of infection	Microorganism	Material
1	Pneumonia/Leptospirosis	Respiratory	Enterobacter sp	Sputum
2	Pneumonia/Suicide attempt (glicosate ingestion)	Respiratory	P. aeruginosa	Sputum
3	Pneumonia/UTI/Diarrhea	Respiratory, Urinary, and Intestinal	Not identified/K. pneumoniae/E. coli OH157	Sputum/Urine/Feces
4	Pneumonia/UTI/DM	Respiratory/Urinary	Streptococcus agalactiae, S. aureus/Staphylococcus sp, E. coli	Blood/Urine
5	Pneumonia	Respiratory	Haemophilus sp	Sputum
6	Septic arthritis	Joint	S. aureus	Sinovial liquid
7	Pneumonia	Respiratory	Not identified	Sputum/Blood
8	Pneumonia	Respiratory	E. coli, Moraxella sp	Sputum
9	Pneumonia/COPD	Respiratory	Not identified	Sputum/Blood
Mechanical ventilation (n = 11)
	Diagnosis
1	Anaphylaxis (anaesthesia)
2	Head trauma
3	Spinal cord trauma
4	Subarachnoid hemorrhage
5	Subarachnoid hemorrhage
6	Intracerebral hemorrhage
7	Anaphylaxis (anaesthesia)
8	Guillain-Barre syndrome
9	Intracerebral hemorrhage
10	Anaphylaxis (anaesthesia)
11	Epilepsy

ARDS, acute respiratory distress syndrome; CNS, central nervous system; COPD, chronic obstructive respiratory disease; DM, diabetes mellitus; SBP, spontaneous bacterial peritonitis; UTI, urinary tract infection.

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