Figure 2

Changes in oxygen delivery index (DO₂I), oxygen extraction rate (O₂-ER) and mixed-venous oxygen saturation (S_vO₂). AVP, arginine vasopressin; AVP-Dobu, group treated with AVP and dobutamine; T1 = healthy baseline, T2 = endotoxemic baseline, T3 = AVP or placebo, T4, T5, T6 = AVP + dobutamine 2, 5 and 10 μg.kg^-1·min^-1 or placebo, respectively, *p < 0.05 versus control, **p < 0.01 versus control, ***p < 0.001 versus control, ^†p < 0.05 versus AVP, ^††p < 0.01 versus AVP, ^†††p < 0.001 versus AVP, ^‡p < 0.05 versus T1, ^‡‡p < 0.01 versus T1, ^§§p < 0.01 versus T4, ^§§§p < 0.001 versus T4, ^∥∥p < 0.01 versus T5, ^∥∥∥p < 0.001 versus T5.