Figure 2
From: Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction
Cellular response. Lung homogenate myeloperoxidase activity (a), bronchoalveolar lavage fluid (BALF) total neutrophils (b), and BALF total cells (c) in mice treated with intraperitoneal PBS followed 14 hours later by 6 hours of spontaneous breathing (PBS) or mechanical ventilation (MV), and in mice treated with intraperitoneal lipopolysaccharide (LPS; 1 μg/kg) followed 14 hours later by either spontaneous breathing (LPS) or 6 hours of mechanical ventilation (LPS + MV). In all groups receiving mechanical ventilation, the tidal volume was 10 ml/kg and the fraction of inspired oxygen was 0.21. *p < 0.05.