Serum neuron-specific enolase as early predictor of outcome after in-hospital cardiac arrest: a cohort study

Table 2 Studies of serum neuron-specific enolase to predict unfavorable outcome after cardiac arrest

Reference	In-hospital CPR	NSE sampling time (hours)	Favorable outcome (n)	Unfavorable outcome (n)	Cut-off value (ng/ml)	Sensitivity (percentage)	Specificity (percentage)
[26]	No	24	45	20	>17	40	98
[23]	Not specified	24	27	35	>20	51	89
[12]	No	72	18	25	>33	65	100
[24]	No	72	28	24	>16.4	70	100
[25]	Yes/No^a	48	34	76	>25	59	100
[13]	Yes/No^b	72	28	69	>65	50	96
[27]	Yes/No^c	24	51^d	356^d	>33	44	100
This study	Yes	12–36	34	9	>60	35	100

CPR = cardiopulmonary resuscitation; NSE = neuron-specific enolase. ^a77% out-of-hospital arrests; ^b56% were out-of-hospital arrests; ^c85% were out-of-hospital arrests; ^dNSE levels were determined in 231 of 407 patients.

ISSN: 1364-8535