The early responses of VEGF and its receptors during acute lung injury: implication of VEGF in alveolar epithelial cell survival

Table 2 Differential patterns of VEGF and VEGFRs immunostaining in the lung cells.

	VEGF			VEGFR-1			VEGFR-2
	Control	Sham	IIR	Control	Sham	IIR	Control	Sham	IIR
Bronchial epithelium (ciliated)	+++	+++	++	+++	+++	++	++	++	++
Bronchial epithelium (non-ciliated)	+++	+++	++	++	++	++	++	++	++
Type I cells	+	+	-	++	+	+	-	-	-
Type II cells	++	++	+	+++	++	+	+	++	++
Interstitial cells	-	-	-	++	+	+	-	-	-
Vascular endothelium	++	++	++	+++	+++	++	+	+	+
Alveolar macrophages	+	+	+	++	+	+	+	+	+

Unstained, -; occasional staining, +; weak to moderate diffuse staining, ++; strong diffuse staining, +++. IIR, intestinal ischemia-reperfusion; VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor.

ISSN: 1364-8535