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Table 2 Physiologic variables immediately after intubation and 24 hours after intubation

From: Biological markers of lung injury before and after the institution of positive pressure ventilation in patients with acute lung injury

Physiologic variables

Within 1 to 2 hours after intubationa

Twenty-four hours after intubationa

p valueb

PaO2/FiO2 ratio

132 ± 71

186 ± 63

0.003

Plateau pressure (cm H2O)

26 ± 8

22 ± 4

0.02

Peak inspiratory pressure (cm H2O)

32 ± 7

27 ± 5

0.02

Positive end-expiratory pressure

6.2 ± 3

7.2 ± 3

0.16

Oxygenation index

12 ± 2

9 ± 2

0.21

Quasistatic respiratory compliance (ml/H2O)

27 ± 12

29 ± 10

0.32

Mean airway pressure (cm H2O)

12 ± 3

12 ± 4

0.53

Tidal volume (ml)

480 ± 120

409 ± 80

0.01

Tidal volume per kg IBW (ml/kg)

8.2 ± 2.2

7.2 ± 1.8

0.02

  1. aData shown as mean ± standard deviation; bpaired t test comparing the pre-intubation and 24-hour post-intubation variables. FiO2, fraction of inspired oxygen; IBW, ideal body weight; PaO2, partial pressure of arterial oxygen.
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Critical Care

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