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Table 1 Main characteristics of young rats and senescent rats treated with lipopolysaccharide (LPS) or saline

From: Endotoxin-induced myocardial dysfunction in senescent rats

 

Young rats (3 months old)

Senescent rats (24 months old)

 

Control group (n = 9)

LPS 0.5 mg/kg group (n = 12)

LPS 5 mg/kg group (n = 9)

Control group (n = 13)

LPS 0.5 mg/kg group (n = 16)

Initial body weight (g)

315 ± 3

331 ± 8

331 ± 5

451 ± 26

459 ± 15

ΔBW (g)

-1 ± 1

-18 ± 2*

-11 ± 3*

-2 ± 2

-16 ± 2*

Liver (g)

12.1 ± 0.8

10.9 ± 0.4

10.1 ± 0.3*

10.9 ± 0.7

9.2 ± 0.4*

Lung (g)

1.30 ± 0.03

1.46 ± 0.04*

1.45 ± 0.03*

4.14 ± 0.47

6.07 ± 0.60*

Heart weight (g)

0.98 ± 0.02

1.09 ± 0.05*

1.10 ± 0.02*

1.34 ± 0.10

1.60 ± 0.10*

Left ventricular weight (g)

0.78 ± 0.02

0.83 ± 0.03

0.85 ± 0.02

1.00 ± 0.07

1.11 ± 0.06

  1. Values are the mean ± standard error of the mean. ΔBW, body weight 12 hours after treatment - initial body weight. *P < 0.05 versus respective control (saline-injected) group.
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