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Figure 1 | Critical Care

Figure 1

From: Bench-to-bedside review: Potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure

Figure 1

Schematic representation of oxidative phosphorylation within the mitochondria. Electrons donated from NADH and FADH2 pass down the electron transport chain with oxygen being the terminal acceptor at complex IV. This movement of electrons results in a shift of protons across the inner mitochondrial membrane, generating the energy necessary for ATP synthase to produce ATP from ADP. FADH2, flavin adenine dinucleotide, reduced; NADH, nicotinamide adenine dinucleotide, reduced.

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