Table 1 Characteristics of patients according to 30-day mortality
30-day mortality | |||
|---|---|---|---|
Variable | Yes (n = 56) | No (n = 94) | P |
Age (years) | 66.4 ± 18.4 | 60.4 ± 17.9 | 0.38 |
Sex (male) | 42 (75.0) | 63 (67.0) | 0.40 |
Charlson score | 4 (2–6) | 3 (2–6) | 0.15 |
Comorbidities | |||
Neurological | 14 (48.3) | 44 (36.4) | 0.33 |
Cardiac | 20 (69.0) | 69 (57.0) | 0.33 |
Pulmonary | 12 (41.4) | 55 (45.5) | 0.85 |
Malignancy | 6 (20.7) | 21 (17.4) | 0.88 |
Diabetes | 10 (34.5) | 29 (24.0) | 0.36 |
Renal | 4 (13.8) | 28 (23.1) | 0.20 |
Cirrhosis | 4 (13.8) | 12 (9.9) | 0.37 |
AIDS | 2 (6.9) | 8 (6.6) | 0.61 |
Immunosuppression | 23 (41.1) | 33 (35.5) | 0.58 |
Other infections | 17 (30.4) | 25 (26.6) | 0.76 |
Previous surgery | 24 (42.9) | 38 (40.4) | 0.90 |
Length of hospital stay (days) | 16.5 (7.5–30) | 15.5 (5–30) | 0.52 |
Severe sepsis or septic shock | 40 (71.4) | 31 (33.0) | <0.001 |
Ventilator-associated pneumonia | 33 (58.9) | 22 (23.4) | <0.001 |
>1 site | 7 (12.5) | 15 (16.0) | 0.73 |
Polymicrobial pneumonia | 23 (41.1) | 30 (31.9) | 0.38 |
Bacteremia | 12 (21.4) | 9 (9.6) | <0.05 |
Appropriate therapy | |||
At any moment | 31 (55.5) | 78 (83.0) | <0.001 |
≤ 24 hours | 11 (19.6) | 35 (37.2) | <0.05 |
Time to initiate appropriate therapy (days) | 4.5 ± 2.1 | 5.1 ± 5.1 | 0.60 |
Combination therapy (n = 109) | 3 (9.7) | 15 (19.9) | 0.18 |