Effect of the molecular adsorbent recirculating system and Prometheus devices on systemic haemodynamics and vasoactive agents in patients with acute-on-chronic alcoholic liver failure

Table 3 Haemodynamic parameters before and after three successive days of standard medical therapy (SMT) alone or treatment with the molecular adsorbent recirculating system (MARS)/Prometheus devices combined with SMT

	Normal range	SMT		MARS + SMT		Prometheus + SMT
		Before treatment	After treatment	Before treatment	After treatment	Before treatment	After treatment
Heart rate (beats/min)	60–100	81 ± 3	81 ± 3	77 ± 7	83 ± 6	86 ± 5	97 ± 6*
Mean arterial pressure (mmHg)	72–102	72 ± 1	66 ± 2**	67 ± 4	76 ± 3**	69 ± 2	69 ± 1
Stroke volume (ml)	70–130	120 ± 16	115 ± 17	107 ± 18	120 ± 15**	107 ± 8	99 ± 11
Central venous pressure (mmHg)	1–9	11 ± 2	10 ± 2	9 ± 2	9 ± 2	10 ± 2	11 ± 2
Cardiac index (ml/min/m²)	2.5–4	5.1 ± 0.4	5 ± 0.4	4.2 ± 0.4	4.5 ± 0.4	5.3 ± 0.5	5.4 ± 0.6
Systemic vascular resistance index (dyn.s/cm⁵/m²)	1760–2600	1008 ± 116	978 ± 134	1088 ± 88.1	1219 ± 93**	934 ± 72	841 ± 62

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