Table 2 Biochemical parameters before and after three successive days of standard medical therapy (SMT) alone or treatment with the molecular adsorbent recirculating system (MARS)/Prometheus devices combined with SMT
| Â | SMT | MARS + SMT | Prometheus + SMT | |||
|---|---|---|---|---|---|---|
| Â | Before treatment | After treatment | Before treatment | After treatment | Before treatment | After treatment |
Ammonia (μM) | 65.6 ± 8.8 | 72.9 ± 9.2 | 57.8 ± 5.3 | 63.7 ± 11.1 | 45.4 ± 3.3 | 49 ± 7.4 |
Bilirubin (mg/dl) | 29.5 ± 4.3 | 29.9 ± 4.4 | 21.8 ± 2.6 | 16.6 ± 1.2* | 29.7 ± 2.9 | 18 ± 3.2** |
Bile acids (μM) | 162 ± 36.7 | 172.7 ± 34 | 111 ± 17.1 | 78 ± 19.7** | 145.3 ± 16.4 | 78.1 ± 14.1** |
Albumin (g/l) | 29 ± 1.7 | 29.8 ± 1.8 | 27.7 ± 0.9 | 28.9 ± 1.3 | 25.7 ± 1.1 | 25.3 ± 1.9 |
Prothrombin activity (%) | 36.8 ± 2.5 | 34.7 ± 3.4 | 39.9 ± 4.2 | 39.8 ± 4.2 | 37.3 ± 5.5 | 28.1 ± 6.1 |
Creatinin (mg/dl) | 1.3 ± 0.4 | 1.4 ± 0.4 | 1.4 ± 0.3 | 1.1 ± 0.2 | 1.2 ± 0.1 | 0.9 ± 0.1 |
Urea (mg/dl) | 66.7 ± 20 | 77.3 ± 21.5 | 64.1 ± 22 | 41.8 ± 13.2 | 51.5 ± 22.3 | 27.8 ± 10.3 |
Leukocyte count (× 109/l) | 12.6 ± 2.6 | 13.8 ± 2.9 | 13.8 ± 1.8 | 13.8 ± 1.7 | 19.5 ± 5.8 | 16.4 ± 2.9 |
C-reactive protein (mg/l) | 33.2 ± 9.7 | 32.3 ± 9.8 | 53.5 ± 9.0 | 58 ± 7.4 | 41.2 ± 7.6 | 31.1 ± 6.7 |