Table 1 Preadmission comorbidities and types admission of the study cohort
From: Corticosteroids influence the mortality and morbidity of acute critical illness
| Â | Control group (n = 7,626) | Corticosteroid exposure group (n = 2,632) | P |
|---|---|---|---|
Age (years) | 72 (48–84) | 67 (43–82) | 0.0001 |
Female | 2,860 (38) | 1,147 (44) | 0.0001 |
Body mass index (kg/m2) | 26 (20–35) | 26 (20–35) | 0.8 |
Peripheral arterial disease | 777 (10) | 221 (8) | 0.008 |
Cerebral vascular disease | 159 (2) | 23 (1) | 0.0001 |
Neurological disease (degenerative brain disease) | 1,048 (14) | 396 (15) | 0.1 |
Congestive heart failure | 974 (13) | 361 (14) | 0.2 |
Hypertension | 3,687 (48) | 995 (38) | 0.0001 |
Diabetes mellitus | 1,359 (18) | 436 (17) | 0.1 |
Liver disease | 636 (8) | 351 (13) | 0.0001 |
Malignancy | 1,179 (15) | 685 (26) | 0.0001 |
Chronic obstructive pulmonary disease | 870 (11) | 565 (21) | 0.0001 |
Pulmonary disease (restrictive and obstructive) | 1,025 (13) | 663 (25) | 0.0001 |
Renal disease | 577 (8) | 223 (8) | 0.9 |
Connective tissue disease | 88 (1) | 197 (7) | 0.0001 |
Cachexia | 157 (2) | 126 (5) | 0.0001 |
Charlson comorbidity score | 1 (0–4) | 2 (0–5) | 0.0001 |
Indications for corticosteroids | Â | Â | Â |
   Relative adrenal insufficiency | - | 1,022 (39) | - |
   Anti-inflammatory action | - | 1,270 (48) | - |
   Immunosuppression | - | 340 (13) | - |
Types of admission | Â | Â | Â |
   Coronary care unit | 1,561 (20) | 211 (8) | 0.0001 |
   Medical | 2,623 (34) | 1,168 (44) | 0.0001 |
   Surgical | 3,442 (46) | 1,253 (48) | 0.1 |