Table 2 Anti-Xa activity before (0 h) and 3, 4, 6, 8, 12 and 24 h after subcutaneous administration of 2,500 IU dalteparin

From: Anti-Xa activity after subcutaneous administration of dalteparin in ICU patients with and without subcutaneous oedema: a pilot study

	Anti-Xa activity (IU/ml)
	0 h	3 h	4 h	6 h	8 h	12 h	24 h	AUC_{(0–24 h)}
Index: with oedema
1	0.01	0.18	0.14	0.03	0.06	0.02	0.01	1.05
2	0.00	0.20	0.17	0.08	0.03	0.00	0.00	0.91
3	0.02	0.15	0.11	0.10	0.04	0.03	0.06	1.42
4	0.06	0.16	0.14	0.12	0.09	0.02	0.04	1.53
5	0.03	0.04	0.02	0.03	0.03	0.02	0.02	0.59
6	0.00	0.14	0.12	0.12	0.10	0.12	0.17	2.98
7	0.10	0.20	-^a	0.11	0.10	0.07	0.03	2.07
Mean (SD)	0.03 (0.02)	0.15 (0.05)	0.12 (0.05)	0.08 (0.04)	0.06 (0.03)	0.04 (0.04)	0.05 (0.06)	1.50 (0.81)
Reference: without oedema
1	0.00	0.09	0.08	0.05	0.01	0.00	0.00	0.43
2	0.01	0.14	0.13	0.09	0.07	0.03	0.02	1.24
3	0.00	0.25	0.16	0.08	0.03	0.00	0.00	0.99
4	0.01	0.10	0.09	0.07	0.05	0.03	0.00	0.88
5	0.04	0.08	0.09	0.09	0.05	0.03	0.02	1.05
6	0.02	0.13	0.09	0.05	0.04	0.02	0.02	0.93
7	0.04	0.18	0.16	0.15	0.12	-^a	0.06	2.52
Mean (SD)	0.02 (0.02)	0.14 (0.06)	0.11 (0.04)	0.08 (0.03)	0.05 (0.03)	0.02 (0.01)	0.02 (0.02)	1.15 (0.65)

^aMissing value. AUC, area under the concentration curve; SD, standard deviation.

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