Table 1 Systemic hemodynamics
Baseline (t0) | Endotoxemia (t1) | Resuscitation (t2) | |
|---|---|---|---|
Mean arterial blood pressure (mmHg) | |||
Nonresuscitation group | 117 ± 6 | 105 ± 13† | 96 ± 19*† |
HES130/0.4 (Voluven®) group | 118 ± 6 | 102 ± 21† | 96 ± 26*† |
HES200/0.5 (HES-STERIL® 6%) group | 119 ± 9 | 105 ± 11† | 114 ± 14 |
Ringer's lactate group | 113 ± 10 | 102 ± 18† | 123 ± 26 |
Control group | 113 ± 4 | 127 ± 3* | 129 ± 6*‡ |
Heart rate (beats/minute) | |||
Nonresuscitation group | 263 ± 21 | 278 ± 27† | 294 ± 30*† |
HES130/0.4 (Voluven®) group | 268 ± 25 | 277 ± 22† | 299 ± 24*† |
HES200/0.5 (HES-STERIL® 6%) group | 252 ± 16 | 269 ± 27* | 295 ± 16*† |
Ringer's lactate group | 247 ± 14 | 264 ± 26* | 280 ± 19*† |
Control group | 261 ± 9 | 248 ± 9* | 256 ± 7‡ |
Central venous pressure (mmHg) | |||
Nonresuscitation group | 3.8 ± 1.3 | 3.9 ± 0.6 | 3.7 ± 0.8 |
HES130/0.4 (Voluven®) group | 4.0 ± 0.9 | 4.0 ± 0.9 | 6.3 ± 1.2*†‡ |
HES200/0.5 (HES-STERIL® 6%) group | 4.2 ± 0.6 | 3.9 ± 0.6 | 6.0 ± 1.5*‡ |
Ringer's lactate group | 3.8 ± 0.9 | 4.0 ± 1.4 | 6.7 ± 1.7*†‡ |
Control group | 4.2 ± 0.9 | 4.5 ± 1.8 | 4.6 ± 1.1 |
Renal blood flow (ml/minute) | |||
Nonresuscitation group | 4.9 ± 0.9 | 2.5 ± 1.1*† | 2.1 ± 1.3*† |
HES130/0.4 (Voluven®) group | 4.8 ± 1.0 | 2.1 ± 0.9*† | 4.9 ± 1.5‡ |
HES200/0.5 (HES-STERIL® 6%) group | 5.4 ± 1.0 | 2.0 ± 0.7*† | 6.7 ± 1.1*†‡ |
Ringer's lactate group | 4.9 ± 0.9 | 3.0 ± 1.2*† | 5.7 ± 1.3*‡ |
Control group | 5.6 ± 0.9 | 5.1 ± 1.0 | 5.1 ± 1.0‡ |
Renal vascular resistance (dyne/s/cm5) | |||
Nonresuscitation group | 26 ± 6 | 50 ± 22*† | 51 ± 22*† |
HES130/0.4 (Voluven®) group | 25 ± 6 | 58 ± 32* | 21 ± 8‡ |
HES200/0.5 (HES-STERIL® 6%) group | 23 ± 5 | 57 ± 22*† | 17 ± 1†‡ |
Ringer's lactate group | 24 ± 7 | 38 ± 9*† | 21 ± 2†‡ |
Control group | 21 ± 3 | 26 ± 5* | 26 ± 5*‡ |